U.S. Food and Drug Administration Center for Drug Evaluation and Research statisticians are designing trials with adaptive features to make clinical evaluation of new drug treatments more efficient and informative. Clinical trials with flexibility and adaptive features are critical for evaluating new treatments during medical emergencies and for diseases, such as cancer.
As part of the U.S. Department of Homeland Security’s (DHS) ongoing efforts to support state, local, tribal, and territorial partners, Secretary Kirstjen M. Nielsen announced final allocations of $345 million for six Fiscal Year (FY) 2018 DHS competitive preparedness grant programs. The FY 2018 preparedness grants focus on the nation’s highest risk areas, and law enforcement and terrorism prevention activities.
The MinION, a handheld genomic sequencer, showed promise in a recent field demonstration as it continues testing at the U.S. Army Research, Development and Engineering Command Chemical & Biological Center. Not only can the MinION detect known threats, it can sequence unknown threats, too. These unknown biothreats include emerging and genetically modified pathogens.
Earthquakes pose a profound danger to people and cities worldwide, but with the right hazard-mitigation efforts, from stricter building requirements to careful zoning, the potential for catastrophic collapses of roads and buildings and loss of human lives can be limited. In a milestone for earthquake forecasting, researchers have come up with a physics-based model that marks a turning point in earthquake forecasting.
Keeping structures operational after an earthquake, hurricane, tornado, or other natural hazard could become more likely with improved standards and codes for the construction of residential and commercial buildings, according to a new report recently delivered to the U.S. Congress by the National Institute of Standards and Technology (NIST).
Every September, the Centers for Disease Control and Prevention (CDC) along with its partners supports emergency preparedness efforts and encourages Americans to take action before, during, and after an emergency. This year, the CDC is highlighting Prepare Your Health. Each week focuses on the roles individuals, state and local public health, and CDC play in creating resilient health communities.
The U.S. Department of Agriculture (USDA) Forest Service announced a new strategy for managing catastrophic wildfires and the impacts of invasive species, drought, and insect and disease epidemics. A new report outlines the Forest Service’s plans to work more closely with states to identify landscape-scale priorities for targeted treatments in areas with the highest payoffs.
The Substance Abuse and Mental Health Services Administration (SAMHSA) has developed new resources and materials with significant input from first responders. Their new, online training course addresses occupational stressors; mental health and substance use issues including depression, posttraumatic stress disorder, suicidality, and alcohol use; resilience; and healthy coping mechanisms including demonstrations of stress management techniques.
Kiran Bhaganagar, from The University of Texas at San Antonio, and her team from Laboratory of Turbulence Sensing and Intelligence Systems, used computer models to replicate the dispersal of chemical gas from the April 4, 2017 chemical weapons attack in northwest Syria. The accuracy of her simulations showed the ability to capture real world conditions despite a scarcity of information.
The human body produces many antimicrobial peptides that help the immune system fend off infection. Scientists hoping to harness these peptides as potential antibiotics have now discovered that other peptides in the human body can also have potent antimicrobial effects, expanding the pool of new antibiotic candidates.